E-ISSN: 2619-9467

Contents    Cover    Publication Date: 19 Apr 2024
Year 2024 - Volume 34 - Issue 1

Open Access

Peer Reviewed

CASE REPORTS
170 Viewed289 Downloaded

Case Report of Vaginal Angiomyofibroblastoma and Differential Diagnosis of Other Benign Mesenchymal Tumors in the Female Genitalia

Full Text PDF  
JCOG. 2024;34(1):36-40
DOI: 10.5336/jcog.2023-97358
Article Language: EN
Copyright Ⓒ 2020 by Türkiye Klinikleri. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
A wide variety of mesenchymal lesions, benign and malignant tumors can involve the vulvovaginal region. However, it is not easy to make a list for differential diagnoses by imaging modalities or gross findings. Angiomyofibroblastoma (AMFB) is a rare, benign mesenchymal tumor. Most cases of AMFB occur in the female genital tract. We reported a case of a 20-year-old female patient with AMFB on the anterior vaginal wall. The patient visited emergency clinic because of sudden vaginal bleeding that progressively increased. Ultrasound and magnetic resonance imaging revealed an approximately 7.7×5.0 cm mass between the cervix and vaginal wall. Incision was made at the anterior vaginal wall and local excision was performed under general anesthesia. She was discharged without complications and vaginal structure was well recovered. In addition, we reviewed other mesenchymal tumors of the female genitalia for their differential diagnosis.
REFERENCES:
  1. Fatusic J, Hudic I, Fatusic Z, Mustedanagic-Mujanovic J. Angiomyofibroblastoma of the vaginal portion. Med Arch. 2014;68(6):424-5. [Crossref]  [PubMed]  [PMC] 
  2. Fletcher CD, Tsang WY, Fisher C, Lee KC, Chan JK. Angiomyofibroblastoma of the vulva. A benign neoplasm distinct from aggressive angiomyxoma. Am J Surg Pathol. 1992;16(4):373-82. [Crossref]  [PubMed] 
  3. Nucci MR. Mesenchymal lesions of the lower genital tract. Surg Pathol Clin. 2009;2(4):603-23. [Crossref]  [PubMed] 
  4. Poljak NK, Kljajić Z, Petricević J, Forempoher G, Simunić MM, Colović Z, et al. Polypoid angiomyofibroblastoma tumor of nasal cavity: case report. Coll Antropol. 2013;37(1):301-4. [PubMed] 
  5. Zhu J, Su S, Li H. Angiomyofibroblastoma of the mediastinum: A case report and literature review. Medicine (Baltimore). 2016;95(48):e5484. [Crossref]  [PubMed]  [PMC] 
  6. Nielsen GP, Young RH, Dickersin GR, Rosenberg AE. Angiomyofibroblastoma of the vulva with sarcomatous transformation ("angiomyofibrosarcoma"). Am J Surg Pathol. 1997;21(9):1104-8. [Crossref]  [PubMed] 
  7. Wang YF, Qian HL, Jin HM. Local recurrent vaginal aggressive angiomyxoma misdiagnosed as cellular angiomyofibroblastoma: A case report. Exp Ther Med. 2016;11(5):1893-5. [Crossref]  [PubMed]  [PMC] 
  8. Lee KA, Seo JW, Yoon NR, Lee JW, Kim BG, Bae DS. Aggressive angiomyxoma of the vulva: A case report. Obstet Gynecol Sci. 2014;57(2):164-7. [Crossref]  [PubMed]  [PMC] 
  9. Dragoumis K, Drevelengas A, Chatzigeorgiou K, Assimakopoulos E, Venizelos I, Togaridou E, et al. Aggressive angiomyxoma of the vulva extending into the pelvis: report of two cases. J Obstet Gynaecol Res. 2005;31(4):310-3. [Crossref]  [PubMed] 
  10. Blandamura S, Cruz J, Faure Vergara L, Machado Puerto I, Ninfo V. Aggressive angiomyxoma: a second case of metastasis with patient's death. Hum Pathol. 2003;34(10):1072-4. [Crossref]  [PubMed] 
  11. Chan MM, Yong TT, Sittampalam K. Giant labial fibroepithelial stromal polyp. Malays J Pathol. 2013;35(1):91-4. [PubMed] 
  12. Iwasa Y, Fletcher CD. Distinctive prepubertal vulval fibroma: a hitherto unrecognized mesenchymal tumor of prepubertal girls: analysis of 11 cases. Am J Surg Pathol. 2004;28(12):1601-8. [Crossref]  [PubMed] 
  13. Maggiani F, Debiec-Rychter M, Verbeeck G, Sciot R. Extramammary myofibroblastoma is genetically related to spindle cell lipoma. Virchows Arch. 2006;449(2):244-7. [Crossref]  [PubMed] 
  14. Mortele KJ, Lauwers GJ, Mergo PJ, Ros PR. Perineal angiomyofibroblastoma: CT and MR findings with pathologic correlation. J Comput Assist Tomogr. 1999;23(5):687-9. [Crossref]  [PubMed] 
  15. Geng J, Hu S, Wang F. Large paravaginal angiomyofibroblastoma: magnetic resonance imaging findings. Jpn J Radiol. 2011;29(2):152-5. [Crossref]  [PubMed]