ABSTRACT
A wide variety of mesenchymal lesions, benign and malignant tumors can involve the vulvovaginal region. However, it is not easy to make a list for differential diagnoses by imaging modalities or gross findings. Angiomyofibroblastoma (AMFB) is a rare, benign mesenchymal tumor. Most cases of AMFB occur in the female genital tract. We reported a case of a 20-year-old female patient with AMFB on the anterior vaginal wall. The patient visited emergency clinic because of sudden vaginal bleeding that progressively increased. Ultrasound and magnetic resonance imaging revealed an approximately 7.7×5.0 cm mass between the cervix and vaginal wall. Incision was made at the anterior vaginal wall and local excision was performed under general anesthesia. She was discharged without complications and vaginal structure was well recovered. In addition, we reviewed other mesenchymal tumors of the female genitalia for their differential diagnosis.