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Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome That Develops After Hysterectomy Surgery
Received: 02 Dec 2022 | Received in revised form: 19 Sep 2023
Accepted: 25 Sep 2023 | Available online: 09 Oct 2023
JCOG. 2023;33(4):245-8
DOI: 10.5336/jcog.2022-94674
Article Language: EN
Article Language: EN
Copyright Ⓒ 2024 by Türkiye Klinikleri. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
DRESS syndrome, ''drug reaction with eosinophilia and systemic symptoms,'' is a hypersensitivity reaction that can lead to severe organ dysfunction and mortality. Increased reactive metabolites are thought to cause an immunological response due to inadequate detoxification of the responsible drug. The drugs with which the reaction is most frequently observed are anticonvulsants and sulfonamides. It can be fatal with the reuse of some groups of drugs. Early diagnosis of the disease and discontinuation of the responsible drug in the early period of the reaction is essential. Systemic steroids are used in treatment, and intravenous immunoglobulin is used when necessary. We have presented a 43-year-old female patient diagnosed with DRESS syndrome who was using nitrofurantoin because of a Double J catheter.
DRESS syndrome, ''drug reaction with eosinophilia and systemic symptoms,'' is a hypersensitivity reaction that can lead to severe organ dysfunction and mortality. Increased reactive metabolites are thought to cause an immunological response due to inadequate detoxification of the responsible drug. The drugs with which the reaction is most frequently observed are anticonvulsants and sulfonamides. It can be fatal with the reuse of some groups of drugs. Early diagnosis of the disease and discontinuation of the responsible drug in the early period of the reaction is essential. Systemic steroids are used in treatment, and intravenous immunoglobulin is used when necessary. We have presented a 43-year-old female patient diagnosed with DRESS syndrome who was using nitrofurantoin because of a Double J catheter.
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