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Evaluation of the Relationship Between the Level of Vitamin D in Maternal Blood and Breast Milk and Postpartum Depression
Received: 18 Feb 2020 | Received in revised form: 12 May 2020
Accepted: 17 May 2020 | Available online: 10 Jun 2020Hilal USLU YUVACIa, Hayrullah YAZARb, Elif KÖSEc, Betül Nur ÇOBANa, Mehmet Musa ASLANa, Esra YAZICId, Nermin AKDEMİRa, Arif Serhan CEVRİOĞLUa
aSakarya University Faculty of Medicine, Department of Obstetrics and Gynecology, Sakarya, TURKEY
bSakarya University Faculty of Medicine, Department of Biochemistry, Sakarya, TURKEY
cSakarya University Faculty of Medicine, Department of Public Health, Sakarya, TURKEY
dSakarya University Faculty of Medicine, Department of Psychiatry, Sakarya, TURKEY
J Clin Obstet Gynecol. 2020;30(2):58-64
DOI: 10.5336/jcog.2020-74215
Article Language: EN
Copyright Ⓒ 2024 by Türkiye Klinikleri. This is an open access article under the CC BY-NC-ND license (
http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
Objective: This study aimed to evaluate the relationship between postpartum depression (PPD) and vitamin D levels in maternal blood and breast milk. Material and Methods: The study included women who presented to a polyclinic between December 2017 and August 2018, 4-6 weeks after having given live birth, who were aged between 18 and 40 years and married, gave birth after a planned single pregnancy, were feeding their baby with only breast milk and stated that they were taking vitamin D supplementation at the dose recommended by the Ministry of Health. The depression status of the women who agreed to participate in the study by signing the volunteer informed consent form was evaluated using the Edinburgh Postpartum Depression Scale (EPDS). Two groups were formed as Group 1: EPDS score <13 (n=44) (without PPD) and Group 2: EPDS score ≥13 (n=31) (with PPD). The vitamin D levels in breast milk and maternal blood in both groups were compared. Results: 75 female patients included in the study had a mean age of 29.80±4.54 years. The mean vitamin D levels in breast milk and maternal blood were found to be 13.26±5.39 ng/mL and 17.14±6.79 ng/mL, respectively. In terms of depression status, no statistically significant difference was found between the groups regarding the serum vitamin D levels and the mean level of vitamin D in breast milk (p=0.463, p=0.847). Conclusion: No significant correlation was determined between the vitamin D levels in maternal blood and breast milk and PPD, while vitamin D was found to be low both in maternal blood and breast milk.
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