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The Incidence of Sarcomas Among PatientsWho Were Operated for Leiomyomas
Lei̇omyoma Ön Tanisiyla Opere Edi̇len Hastalarda Sarkom İnsi̇dansi
Okan Murat AKTÜRK*, Orhan AKSAKAL*, Mustafa OZAT*, Ümit BİLGE*, Oya GÖKMEN*
* Zekai Tahir Burak Womens Health Education and Research Hospital, Ankara, Turkey
Turkiye Klinikleri J Gynecol Obst. 2001;11(5):397-400
Article Language: TR
Copyright Ⓒ 2024 by Türkiye Klinikleri. This is an open access article under the CC BY-NC-ND license (
http://creativecommons.org/licenses/by-nc-nd/4.0/)
ÖZET
Amaç: Benign sebeplerle histerektomi ve myomektomi geçiren hastalarda sarkoma insidansını saptamak. Materyel ve Metod: Zekai Tahir Burak Kadın Sağlığı Eğitim ve Araştırma Hastanesinde Ocak 1995 ile Ocak 2000 tarihleri arasında leiomyoma ön tanısıyla opere edilmiş olan 1438 hastanın dosyası geriye dönük incelendi. Leiomyosarkom, endometrial stromal sarkom ve malign miks Müllerian tümör insidansları araştırıldı. Hastaların yaşları, başvuru semptomları, preoperatif, operatif bulguları ve patoloji raporları incelendi. Sonuçlar: Genel sarkom insidansı %0.42 olarak bulundu (6 hasta). Leiomyosarkom insidansı %0.07 olarak bulundu (bir hasta). Üç hastada (%0.2) düşük gradeli endometrial stromal sarkom saptandı. Bir hastada (%0.07) malign mikst Mullerian tümör bulunurken, bir hastada da (%0.07) türü belirlenemeyen düşük mitotik indeksli malign mezenşimal tümör saptandı. Myomektomi yapılan 98 ve vajinal histerektomi yapılan 100 hastada ise herhangi bir malignite saptanmadı. Sonuç: Leiomyoma sebebiyle opere edilen hastalarda sarkom insidansı oldukça düşüktür. Bunların da çoğu düşük mitotik indeksli ve düşük gradelidirler.
ABSTRACT
Objective: To determine the incidence of sarcoma in patients who had myomectomies and hysterectomies for benign reasons. Materials and Method: We reviewed the files of 1438 patients who had been operated for presumed benign leiomyomas between January 95 and January 2000 in Zekai Tahir Burak Women Health Training and Research Hospital. The incidences of leiomyosarcoma, endometrial stromal sarcoma and malignant mixed Mullerian tumor were investigated. The ages of the patients, presenting symptoms, the preoperative, intraoperative, operative and final pathological findings were reviewed. Results: The overall sarcoma incidence was 0,42% (6 cases) in the study group of 1438 patients. The incidence of leiomyosarcoma was 0,07 % (one patient). Three (0,2%) of the patients had low grade endometrial stromal sarcoma. One (0,07%) patient had malignant mixed mullerian tumor. One (0,07%) patient had malignant mesenchymal tumor with low mitotic index. Among the 98 myomectomies no sarcomas were diagnosed and among the 100 vaginal hysterectomies no sarcomas were diagnosed pathologically, either. Conclusion: The incidence of sarcoma among the patients underwent surgery for leiomyoma is very low. Furthermore, most of these sarcomas identified are low grade tumors.