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Successful Management of a Cervical Pregnancy with Methotrexate by Systemic Route in a Intraamniotic Methotrexate Resistant Pregnant: Case Report
Servikal Gebelikte İntra-Amniyotik Metotreksat Tedavisine Dirençli Olguda, Başarılı Sistemik Metotreksat Tedavisi
Kerem Doğa SEÇKİNa, İlkin Mahmut YERALa, Eralp BAŞERa, Cihan TOĞRULa, Ahmet Nuri DANIŞMANa
aClinic of Obstetrics and Gynecology, Zekai Tahir Burak Women's Health Training and Research Hospital, Ankara
Turkiye Klinikleri J Gynecol Obst. 2013;23(2):138-40
Article Language: EN
Copyright Ⓒ 2024 by Türkiye Klinikleri. This is an open access article under the CC BY-NC-ND license (
http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
A-23 years-old woman Gravida: 2, Para: 0, Abortion: 1 applied to us with painless minimal vaginal bleeding and delayed menstrual period. The ultrasound imaging performed and in the cervical canal there was a pregnancy which has crown-rump lenght (CRL): 2.3 mm 5 weeks and 5 days and fetal cardiac activity. The same day it was decided to administer intra-amniotically methotrexate (75 mg) under ultrasonographic guidance. Controls of BHCG levels didn't decrease as much as we expected. A single dose of 75 mg of systemic MTX was given on day 15. A case report of diagnosis and successful treatment of cervical pregnancy which is treated systemic MTX after intra-amniotic MTX was described.
ÖZET
23 yaşında gravida: 2, parite: 0, abort: 1 olan kadın hasta bize gecikmiş menstrüasyon ve minimal vajinal kanama şikayetiyle başvurdu. Yapılan ultrasonun görüntülemesinde servikal kanalda baş-popo uzunluğu (CRL): 2,3 milimetrelik 5 hafta 5 gün ile uyumlu, fetal kardiyak aktiviteye sahip fetüs mevcttu. Aynı gün hastaya ultrason eşliğinde 75 mg intra-amniyotik metotreksat (MTX) enjeksiyonu yapıldı. Kontrol BHCG seviyeleri düşmedi. Hastaya 15. gününde 75 mg tek doz sistemik MTX verildi. Bu olgu sunumunda intra amniyotik MTX tedavisinden sonra uygulanan sistemik MTX ile başarılı şekilde tedavi edilmiş servikal gebelik tanımlanmıştır.