E-ISSN: 2619-9467

Contents    Cover    Publication Date: 12 Nov 2020
Year 2020 - Volume 30 - Issue 3

Open Access

Peer Reviewed

ORIGINAL RESEARCH
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Superb Microvascular Imaging (SMI) - Doppler Technique in the Evaluation of the Endometrial Polyp and Submucosal Myoma in Postmenopausal Overweight Women

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J Clin Obstet Gynecol. 2020;30(3):106-12
DOI: 10.5336/jcog.2020-75635
Article Language: EN
Copyright Ⓒ 2020 by Türkiye Klinikleri. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
Objective: The aim of this study was to evaluate postmenopausal endometrial polyp (EP) and submucosal myoma (SMM) vascularity with two-dimensional transabdominal ultrasonography (TAUSG) - Superb Microvascular Imaging (SMI) Doppler and to correlate with histopathological findings. Material and Methods: 11 cases with postmenopausal bleeding and increased endometrial thickness were included in the study. Endometrial vascularity was assessed by TAUSG with conventional and SMI Doppler and Vascularity Index (VI) was calculated. The number of vessels and histopathological findings were correlated. Results: VI was 0.2 (0-2) ± 0.6 in conventional colour Doppler, 0.2 (0-2) ± 0.6 in power Doppler, 2.5 (0-8) ± 3 in colour-SMI and 3.8 (0-12) ± 4.2 in monochrome SMI. VI was found to be significantly lower in the traditional Doppler group than the SMI Doppler group (p=0.018). Pathological examination revealed EP in 8 patients (72.7%) , SMM in three patients (27.2%).In the comparison of the number of vessels observed in the VI and pathological sections, the rate of capturing the vessels was significantly lower in the traditional, colour and monochrome SMI Doppler groups (p=0.03, p=0.07, p=0.016). In the correlation between Body Mass Index and VI, VIs were found to be low in all cases and there were no statistically significant differences between the traditional, colour and monochrome SMI Doppler measurements and weight measurements (p=0.2273, p=0.848, p=0.999). Conclusion: We found that TAUSG-SMI Doppler may be not enough for imaging of lesion vascularity. Uterus is a deeply located organ so trans abdominal route may be not be a proper option in overweight women.
REFERENCES:
  1. Kabil Kucur S, Temizkan O, Atis A, Gozukara I, Uludag EU, Agar S, et al. Role of endometrial power Doppler ultrasound using the international endometrial tumor analysis group classification in predicting intrauterine pathology. Arch Gynecol Obstet. 2013;288(3):649-54. [Crossref]  [PubMed] 
  2. Şenyuva İ, Küçük Ş, Turan Ç, Yüksel G, Şentürk S, Çam Ç, et al. Uterin fibroidlerin vaskülarizasyonu: SMI (Superb Microvascular Imaging) Doppler ultrasonografi bulgularının histopatolojik korelasyonu. Perinatoloji Dergisi. 2018;26(Suppl):16-9.
  3. Hasegawa J, Suzuki N. SMI for imaging of placental infarction. Placenta. 2016;47:96-8. [Crossref]  [PubMed] 
  4. Leone FPG, Timmerman D, Bourne T, Valentin L, Epstein E, Goldstein SR, et al. Terms, definitions and measurements to describe the sonographic features of the endometrium and intrauterine lesions: a consensus opinion from the International Endometrial Tumor Analysis (IETA) group. Ultrasound Obstet Gynecol. 2010;35(1):103-12. [Crossref]  [PubMed] 
  5. Kupesic S, Kurjak A, Hajder E. Ultrasonic assessment of the postmenopausal uterus. Maturitas. 2002;25;41(4):255-67. [Crossref]  [PubMed] 
  6. Dowdy SC, Mariani A, Lurain JR. uterus Kanseri. Berek JS. Jinekoloji. 1. Baskı. Erk A, Demirtürk F, çeviri editörleri. İstanbul: Nobel Tıp Kitabevi; 2017. p.1250-303.
  7. Türkiye Endokrinoloji ve Metabolizma Derneği. Obezite Tanı ve Tedavi Kılavuzu. 8. Baskı. Ankara: BAYT; 2019. p.112. [Crossref] 
  8. Tartaroğlu C, Polat A, Kargı A, Şengiz S, Çamdeviren H, Küpelioğlu A, et al. [Association of macrophages, eosinophil leukocytes and NK cells with angiogenesis and depth of invasion in colorectal carcinomas]. Turkish Journal of Pathology. 2005;21(3-4):49-53.
  9. Prabhu SJ, Kanal K, Bhargava P, Vaidya S, Dighe MK. Ultrasound artifacts: classification, applied physics with illustrations, and imaging appearances. Ultrasound Q. 2014;30(2):145-57. [Crossref]  [PubMed] 
  10. Rumack CM, Wilson SR, Charboneau JW. Diagnostic Ultrasound. 2nd ed. St. Louis: Mosby; 1998. p.1860.
  11. Hamper UM, DeJong MR, Caskey CI, Sheth S. Power Doppler imaging: clinical experience and correlation with color Doppler US and other ýmaging modalities. Radiographics. 1997;17(2):499-513. [Crossref]  [PubMed] 
  12. Jiang ZZ, Huang YH, Shen HL, Liu XT. Clinical applications of superb microvascular imaging in the liver, breast, thyroid, skeletal muscle, and carotid plaques. J Ultrasound Med. 2019;38(11):2811-20. [Crossref]  [PubMed] 
  13. Kamaya A, Yu PC, Lloyd CR, Chen BH, Desser TS, Maturen KE. Sonographic evaluation for endometrial polyps: the interrupted mucosa sign. J Ultrasound Med. 2016;35(11):2381-7. [Crossref]  [PubMed] 
  14. Nijkang NP, Anderson L, Markham R, Manconi F. Endometrial polyps: pathogenesis, sequelae and treatment. SAGE Open Med. 2019;2;7:2050312119848247. [Crossref]  [PubMed]  [PMC] 
  15. Giordano G, Gnetti L, Merisio C, Melpignano M. Postmenopausal status, hypertension and obesity as risk factors for malignant transformation in endometrial polyps. Maturitas. 2007;20;56(2):190-7. [Crossref]  [PubMed] 
  16. Cohen MA, Sauer MV, Keltz M, Lindheim SR. Utilizing routine sonohysterography to detect intrauterine pathology before initiating hormone replacement therapy. Menopause. 1999;6(1):68-70. [Crossref]  [PubMed] 
  17. Reslová T, Tosner J, Resl M, Kugler R, Vávrová I. Endometrial polyps. A clinical study of 245 cases. Arch Gynecol Obstet. 1999;262(3-4):133-9. [Crossref]  [PubMed] 
  18. Nogueira AA, Dos Reis FJC, Silva JCRE, Poli Netto OB, de Freitas Barbosa H. Endometrial polyps: a review. J Gynecol Surg. 2007;23(3):111-6. [Crossref] 
  19. Lieng M, Qvigstad E, Dahl GF, Istre O. Flow differences between endometrial polyps and cancer: a prospective study using intravenous contrast-enhanced transvaginal color flow Doppler and three-dimensional power Doppler ultrasound. Ultrasound Obstet Gynecol. 2008;32(7):935-40. [Crossref]  [PubMed] 
  20. Lasmar RB, Dias R, Barrozo PRM, Oliveira MAP, Coutinho EDSF, da Rosa DB. Prevalence of hysteroscopic findings and histologic diagnoses in patients with abnormal uterine bleeding. Fertil Steril. 2008;89(6):1803-7. [Crossref]  [PubMed] 
  21. Benda JA. Pathology of smooth muscle tumors of the uterine corpus. Clin Obstet Gynecol. 2001 ;44(2):350-63 [Crossref]  [PubMed] 
  22. Elfayomy AK, Habib FA, Elkablawy MA. Role of hysteroscopy in the detection of endometrial pathologies in women presenting with postmenopausal bleeding and thickened endometrium. Arch Gynecol Obstet. 2012;285(3):839-43. [Crossref]  [PubMed] 
  23. Erdem B, ŞIK BA, Tekin B, Özdemir Y, Salman S. [Analysis of the reasons for postmenopausal bleeding that originated from the uterus]. JAREM. 2016;6:78-83. [Crossref] 
  24. Jorizzo JR, Riccio GJ, Chen MY, Carr JJ. Sonohysterography: the next step in the evaluation of the abnormal endometrium. Radiographics. 1999;19:117-30. [Crossref]  [PubMed] 
  25. Laifer-Narin SL, Ragavendra N, Lu DS, Sayre J, Perrella RR, Grant EG, et al. Transvaginal saline hysterosonography: characteristics distinguishing malignant and various benign conditions. Am J Roentgenol. 1999;172(6):1513-20. [Crossref]  [PubMed] 
  26. Bhaduri M, Tomlinson G, Glanc P. Likelihood ratio of sonohysterographic findings for discriminating endometrial polyps from submucosal fibroids. J Ultrasound Med. 2014;33(1):149-54. [Crossref]  [PubMed] 
  27. Cogendez E, Eken MK, Bakal N, Gun I, Kaygusuz EI, Karateke A, et al. The role of transvaginal power Doppler ultrasound in the differential diagnosis of benign intrauterine focal lesions. J Med Ultrason (2001). 2015;42(4):533-40. [Crossref]  [PubMed] 
  28. Davis PC, O'Neill MJ, Yoder IC, Lee SI, Mueller PR. Sonohysterographic ?ndings of endometrial and subendometrial conditions. Radiographics. 2002;22(4):803-16. [Crossref]  [PubMed] 
  29. Alcázar JL, Castillo G, Mínguez JA, Galán MJ. Endometrial blood ?ow mapping using transvaginal power Doppler sonography in women with postmenopausal bleeding and thickened endometrium. Ultrasound Obstet Gynecol. 2003;21(6):583-8. [Crossref]  [PubMed] 
  30. Cil AP, Tulunay G, Kose MF, Haberal A. Power Doppler properties of endometrial polyps and submucosal fibroids: a preliminary observational study in women with known intracavitary lesions. Ultrasound Obstet Gynecol. 2010;35(2):233-7. [Crossref]  [PubMed]