ÖZET
Amaç: Çalışmanın amacı postmenopozal hastalarda günlük tek doz oral estriol tedavisinin endometriuma etkisinin değerlendirilmesi. Materyel ve Metod: 24 postmenopozal hastaya 6 ay süreyle 6 mg/gün estriol süksinat verildi. Tedavi sonunda endometrial kalınlık (ultrasonografi ile) ve endometrial patoloji tedavi almayan kontrol grubuyla karşılaştırıldı. Bulgular: Endometrium tedavi verilen hastaların tümünde ve kontrol grubunda atrofik olarak bulundu. Sonuç: Postmenopozal kadınlarda günlük tek doz estriol tedavisinin endometriuma etkisi yoktur.

ABSTRACT
Objective: The aim of this study was to evaluate the effect of daily single dose oral estriol succinate treatment on endometrium in postmenopausal women. Material and Methods: 24 postmenopausal women received 6 mg estriol succinate daily for six months. At the end of this course of therapy endometrial thickness (evaluated via ultrasonography) and endometrial pathology was compared with the control group who received no medication. Results: The endometrium was atrophic in all cases of treated group same as the control group. Conclusion: Orally once a day estriol has no effect on endometrium in postmenopausal women.