The Relationship Between Idiopathic Heavy Menstrual Bleeding and Periodontitis: A Case-Control Study
Received: 29 Jul 2024 | Received in revised form: 25 Jan 2025
Accepted: 10 Feb 2025 | Available online: 21 Feb 2025Ülkü METE URALa , Gülbahar USTAOĞLUb , Zeynep KARAŞb , Emre AVCIc
aBolu Abant İzzet Baysal University Faculty of Medicine İzzet Baysal Training and Research Hospital, Department of Gynecology and Child Unit Gynecology and Obstetrics, Bolu, Türkiye
bBolu Abant İzzet Baysal University Faculty of Dentistry and Hospital, Department of Periodontology, Bolu, Türkiye
cGülhane University of Health Sciences Faculty of Pharmacy, Department of Basic Pharmaceutical Sciences, Department of Biochemistry, Ankara, Türkiye
JCOG.
DOI: 10.5336/jcog.2024-104999
Article Language: EN
Copyright Ⓒ 2025 by Türkiye Klinikleri. This is an open access article under the CC BY-NC-ND license (
http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
Objective: The cause of idiopathic heavy menstrual bleeding has not been identified, but increased systemic inflammation may be a factor. Periodontitis has an impact on general health and may cause systemic low-grade inflammation. The aim of the study was to investigate the relationship between idiopathic heavy menstrual bleeding and periodontitis. Material and Methods: This study was conducted in the period from January 2020 to January 2024 and a total of 60 women were included. 30 women with idiopathic heavy menstrual bleeding constituted the study group, and 30 healthy age-matched participants with normal menstrual bleeding constituted the control group. Evaluation of menstruation was performed using a pictorial-based assessment chart (PBAC) score. Periodontal status was evaluated with the gingival index, plaque index, bleeding on probing, probing depth, clinical attachment loss, total teeth number, and decay teeth number. Saliva samples were obtained to analyze of total antioxidant status, total oxidant status, arylesterase activity, and oxidative stress index (OSI) levels. Results: There were no statistically significant differences in age and body mass index between the study and the control groups. Median PBAC score and median length of menstrual bleeding were higher in the idiopathic heavy menstrual bleeding group (p