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Borderline Endometrioid Adenocarcinoma of the Ovary Arising in Endometriosis During Tamoxifen Therapy of Postmenopausal Breast Cancer
Postmenopozal Meme Kanseri̇ Tedavi̇si̇nde Kullanilan Tamoksi̇fen İle Endometri̇osi̇s Zemi̇ni̇nde Geli̇şen Over Borderli̇ne Endometri̇oi̇d Adenokanseri̇
Tufan BİLGİN*, Nedret KOLSAL**, Candan CENGİZ*, Ömer YERCİ***
*, Department of Obstetrics and Gynecology, Uludağ University Faculty of Medicine**, Department of Obstetrics and Gynecology, Uludağ University Faculty of Medicine***, Department of Pathology, Uludağ University Faculty of Medicine, Bursa, TURKEY
Turkiye Klinikleri J Gynecol Obst. 2003;13(2):152-4
Article Language: TR
Copyright Ⓒ 2024 by Türkiye Klinikleri. This is an open access article under the CC BY-NC-ND license (
http://creativecommons.org/licenses/by-nc-nd/4.0/)
ÖZET
Amaç: Meme kanseri tedavisinde yaygın kullanılan tamoksifenin antiestrojenik aktivitesi vardır.Estrojenik ortamın düşük olduğu postmenopozal kadınlarda zayıf estrojenik aktivite gösterebilir.Olgu Sunumu: Meme kanseri nedeniyle tamoksifen almakta olan 75 yaşındaki hastada endometriosis zemininde gelişen over borderline endometrioid adenokanser olgusu sunuldu.Sonuç: Kistin cerrahi sırasında rüptürüne bağlı olarak cerrahi evre I C olarak evrelendirildi. Beş yıl sonra hasta sağ ve hastalıksız olarak yaşamını sürdürmektedir.
ABSTRACT
Objective: Tamoxifen has antiestrogenic activity and widely used to treat breast cancer. It also exerts weak estrogenic activity in postmenopausal women where estrogenic environment is low.Case Report: A 75 year old woman receiving tamoxifen for her breast cancer developed a borderline endometrioid adenocarcinoma of the ovary arising in endometriosis is presented.Conclusion: She was surgically staged as I C due to surgical rupture of the cyst. She is well and free of disease after five years.